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It's a "downstream" approach acting at the tissue where fat is stored

Dietary intake of cobalamin in elderly people who have abnormal serum cobalamin, methylmalonic acid and homocysteine levels

doi:10.3389/fimmu.2018.01302

Available data to date from case reports and case series have not identified a Dupixent-related risk of miscarriage, birth defects, or adverse maternal or fetal outcomes