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Short-time infusion of oxaliplatin in combination with capecitabine (XELOX30) as second-line therapy in patients with advanced colorectal cancer after failure to irinotecan and 5-fluorouracil

doi: 10.1016/j.ijpharm.2019.118642 25 SetchellKDBrownNMZimmer-NechemiasLBrashearWTWolfeBEKirschnerASet al

Goal: Amplify the bodys own pulsatile GH release by pairing a GHRH analog (CJC-1295 no DAC) with a GHRP (Ipamorelin) an acute, pharmacologically reasonable synergy

hWJC characterization and transplantation hWJCs were characterized by flow cytometric analysis of hWJC-associated cell surface markers, as previously described [11]

Another potential strategy that can exploit copper-induced cell death is induction of ROS generation