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Apoptotic cell bodies: Lymphocytes from SLE patients frequently experience accelerated apoptosis, releasing nuclear antigens like nucleosomes into the extracellular space, which can then trigger immune responses and autoantibody formation (84)

doi: 10.14719/pst.1621 194 SrivastavaS.SrivastavaA

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Among previously suggested pathways are lipotoxicity arising from ectopic accumulation of fat in tissues other than adipose, such as liver and muscle (Mantzaris et al., 2011