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Ans: Yes, they can, especially if underlying causes like sun exposure, poor sleep, or genetics are not managed

Male mice were used in all studies and sacrificed by exposure to carbon dioxide at different post-natal weeks: 8 (pre-symptomatic phase), 12 (disease onset), and 18 (late symptomatic phase) 18

Sjodin A, Gasteyger C, Nielsen AL, Raben A, Mikkelsen JD, Jensen JK, et al

Davis, Mark D.P

(2014), salivary MDA content in smokers was found to be significantly higher compared to the control group and the group of passive smokers, which was partially compliant with the findings of other research groups (Guentsch et al., 2008