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Elevated plasma iron levels, in turn, lead to an increase in iron transport into parenchymal cells, particularly hepatocytes, pancreatic cells, and cardiomyocytes, leading to organ iron overload

Other reports have described clinical improvement and relatively longer survival in hepatocyte- transplanted patients [143] but poor final outcome has also been reported, possibly related to immunosuppression, inadequate number of transplanted cells, and limited engraftment time [137]

Bartk G, Vradi H, Simon L, Linka E, Tske T, Szab T, et al

Wang C, He L, Xing Y, Zhou W, Yang F, Chen X, Zhang Q

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