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Its uptake by the reticuloendothelial system is low, and its functionalization on graphene sheets leads to high aqueous solubility and physiological stability, as well as reduced toxicity (Charmi et al., 2019

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Figure 8: Effect of cannabis extract alone or in combination with piracetam, vinpocetine, Ginkgo biloba , donepezil or scopolamine on brain malondialdehyde (MDA), reduced glutathione (GSH), nitric oxide and glucose in mice