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Essentially, the FDA has not formally evaluated this exact mixture for safety/efficacy, but each ingredients effects are well-known

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The investigators responsible for drug administration, behavioral testing, and outcome assessment were blinded to the group allocation throughout the experiment.To minimize batch effects, all surgical procedures were performed in a randomized order each day

4 integrates extracellular stress and growth cues to regulate cell-cycle progression, apoptosis, and differentiation, and frequently cooperates with NF-B signaling to promote cancer cell survival and metastasis