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Availability: InStock
Rating: 4.697500000000001 (7 reviews)

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Description

Studies using adult human peripheral T cells demonstrated that glutamate at low concentrations ( 1 mM), however, this effect reversed, indicating that glutamate tends to have immunosuppressive properties at higher concentrations (176, 178)

Cellular Signal 40:99115

However, ICIs should be permanently discontinued if patients have grade 4 irAEs, with the exception of endocrinopathies that are controlled with hormone replacement