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The applicant acknowledged that the device involved in this study was not the VersaVue TM Single-Use Flexible Cystoscope but asserted that this situation is identical to the Uretero1 TM transitional pass-through evaluation and approval

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However, after irradiation, GPx1-KO and wild-type mice exhibited almost similar levels of intestinal GPx activity, and this was due to the radiation-induced compensatory upregulation of GPx2 in GPx1-KO mice