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However, scientific studies do not show a consistent pattern of dysfunctional cortisol levels with adrenal fatigue and in fact the adrenals response to being stimulated by the control hormone ACTH, is still very much positive

On this basis, several therapeutic strategies targeting key pathogenic mechanisms involved in fibrogenesis are being evaluated, including inhibitors of galectin 3, leukotrienes, caspases, Hedgehog signalling and lysyl oxidase-like 2 (LOXL2)

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