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Protocol [2] Female A/J mice are randomized into eight groups (n=8): (i) control

Metformin reduces the levels of lipid peroxidation products such as MDA and 4-hydroxy-2-nonenal (HNE), decreases intracellular ROS levels, and improves mitochondrial function, thereby inhibiting ferroptosis and alleviating the progression of DCM (125)

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Ne iznenauje nas zato, jer se povezuje sa problemom koji pogaa svaku petu osobu na planeti, a od ukupne svetske populacije se ak 40% odraslih bori sa tim

Hepatic lipid metabolism requires a series of key enzymes to be involved in lipid anabolism, lipid catabolism, and fatty acid transporters, including ACC, ELOVL5, ATGL, and FATP1