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A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variant

Mechanisms underlying cardiac protection include enhanced coronary angiogenesis, antioxidant effects reducing oxidative damage, anti-inflammatory modulation limiting inflammatory cell infiltration, and direct cardiomyocyte protection

This creates a vicious cycle that exacerbates inflammation and mitochondrial dysfunction, ultimately contributing to atheroma formation

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Despite these complications, she maintained normal liver function and preserved fertility options through assisted reproductive counseling