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Nevertheless, a particular advantage of these vaccines is that in addition to antibody and CD4 + T cell responses, DNA or RNA vaccine elicit CD8 + cytotoxic T cell responses, which plays a key role for virus eradication 41,42

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[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Jiang M., Bai M., Lei J., Xie Y., Xu S., Jia Z., Zhang A

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To avoid this false positive, we introduce an outgroup (O) to generate a scaled statistic tit which is defined as tit = dXY/(dXO + dYO)