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This is due to the mechanism of RNA interference, which relies on sequence-specific interactions, even slight matches between the RNAi sequence and non-target organism genes could lead to unintended gene silencing

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Ceramides mediate insulin-induced impairments in cerebral mitochondrial bioenergetics in ApoE4 mice

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Emerging data indicate that -syn aggregates not only contribute to mitochondrial damage but also directly or indirectly induce genomic DNA damage

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[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Deng, Z

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