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The mechanisms of low testosterone levels could be due to the down-regulation of the protein expressions of CYP11A1 and CYP 19C in both livers and testes

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Recent studies have highlighted the role of exosome circRNAs and lncRNAs in mediating cell-to-cell communication within the tumor microenvironment, further underscoring their potential as biomarkers and therapeutic targets in cancer (67)

ERRs are members of the nuclear receptor superfamily of ligand-activated transcription factors, though unlike most nuclear receptors, ERRs are constitutively active and were long thought to be "orphan" receptors lacking endogenous ligands

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