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To maintain a cellular steady state in which the majority of proteins are optimally functioning, a robust quality control system, known as protein homeostasis, has evolved to regulate the synthesis, trafficking, localizations, concentrations, interactions, degradation and conformations of these molecules ( In this article, we discuss how the protein homeostasis system does work in isolation, but in coordination with the corresponding systems that regulate the behavior of the other cellular components, including lipids, nucleic acids, carbohydrates and metabolites

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Similar content being viewed by others Introduction One of the grand challenges of our times is the rising prevalence of metabolic syndrome 1

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L-carnitine works through the same core mechanism in bothtransporting fat into cells for energy