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Accessed January 21, 2025

for example, H 2 O 2 can generate hydroxyl radicals ( OH) by reacting with Fentons reagent, and peroxynitrite anions (ONOO ) by reacting with nitric oxide ( 2 O 2 to water ( 3.2 The compromised antioxidant defense system in stroke Increased levels of OS (free radicals) in the brain lead to cerebrovascular and neurodegenerative diseases

The effect of curcumin on global hypo-methylation of DNA was not observed as it did not modify the methylation pattern of long interspersed nuclear elements-1 (LINE-1) in human colon cancer cells

Nevertheless, high inflammation in smokers correlated with emphysema development ( SFTPB, SFTPD, SCNN1A , and SCNN1B gene expression, related to surfactant production and alveolar fluid clearance in ATII cells ( Increasing evidence indicates that the nuclear hormone receptor PPAR, a regulator of lipid metabolism, adipogenesis, and inflammation, represents a potential therapeutic target for emphysema