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Radiation necrosis (RN) may occur from months to years following treatment, affecting a reported 324% of patients [13]

PMID: 10707891

The thresholds reported in preclinical literature vary: PCB-157 : 10 g/kg to 1 mg/kg subcutaneously or intraperitoneally depending on the model

These factors are important to consider in the quest to enhance antiaging influences and expand the healthspan of humans in the future [9, 16]

In ALS, mutant SOD1 in astrocytes causes them to secrete a toxin that selectively kills motor neurons, and transplantation experiments show that wild-type astrocytes can slow ALS progression whereas mutant astrocytes accelerate it