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He had brain swelling, so doctors drilled a hole in his skull to relieve the pressure

Glutamine efflux is preferably mediated by the Slc38a3 system N glutamine transporter, much more so than by one other system N transporter Slc38a2, as the latter shows relatively high affinity for serine, alanine, and glycine (Nakanishi et al., 2001a,b