glutathione breakdown to sulfur Potential Role of Sulfur-Containing Antioxidant Systems in Highly Oxidative Environments The Science Behind the Sulfur

The oxidative burst is instrumental in initiating inflammatory pathways, notably the activation of the NLRP3 inflammasome, which subsequently results in the secretion of potent pro-inflammatory cytokines such as IL-1 and IL-18 (Chen et al., 2025)

A cutoff value of 10.2 nmol/mg for GSH was identified, and the area under the ROC curve was 0.913, with a sensitivity of 90.2% and a specificity of 81.8%, demonstrating significant predictive capability in differentiating between the resistant group and sensitive group

[ Google scholar ] Kang YA, Choi HR, Na JI, Huh CH, Kim MJ, Youn SW, et al

What we care about most, though, are interventional studies, where people are randomized to B12 so we can see what happens

Lvesque, S