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Abbreviations The following abbreviations are used in this manuscript: BALF Bronchoalveolar Lavage Fluid BW Body Weight CINC Cytokine-induced neutrophil chemoattractant CXCL Chemokine Ligand FTIR Fourier-transform infrared IL Interleukin GPX4 Glutathione peroxidase 4 FTH1 Ferritin heavy chain 1 MNP Micro- and nanoplastic MMP Matrix Metalloproteinase MP Microplastic NLRP3 Nod-like receptor family pyrin domain containing 3 NP Nanoplastic PE Polyethylene PET Polyethylene terephthalate PP Polypropylene PS Polystyrene PVC Polyvinyl Chloride ROS Reactive Oxygen Species TLR Toll Like Receptor TGF Transforming Growth Factor TNF Tumor Necrosis Factor Footnotes Conflicts of Interest: The authors declare no conflicts of interest

WHO, 2017)

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Exogenously delivered miR-30e-5p phenocopied the increased atherosclerosis in EC- Slc7a11 -/- mice