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* Correspondence: Kejian Li, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

It is noted that rat metabolism differs from man, and therefore the results of rat studies should be verified in man before the results are extrapolated

Withdrawal is distinct from simple rebound of the original condition rebound symptoms are usually a transient intensification of pre-existing anxiety or insomnia, whereas benzodiazepine withdrawal syndrome involves additional new symptoms

Jun MaTao Zhang, Zhonglin Chen, Minghao Sui, Xueyuan Li

GH secretagogues stimulate upstream signaling that can increase endogenous GH release, while HGH directly supplies the hormone