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Preliminary results on 30 patients showed a 42% improvement in the ECCA scarring score after three sessions of microneedling combined with GHK-Cu + PRP, versus 28% with PRP alone

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Key enzymes, including erythrose-4-phosphate dehydrogenase ( Epd ), 4-phosphoerythronate dehydrogenase ( PdxB ), and 3-phosphoserine aminotransferase ( SerC ), converts erythrose-4-phosphate into 4-phosphohydroxy-l-threonine

Discrepant observations by different research groups make this problem very controversial