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Controversies in the Surgical Management of Thyroid Cancer (Moderators: Tufano R and Parangi S)

Inhibitory kappa B kinase beta (IKK), known as IKK2, is a key regulatory kinase responsible for the activation of NF-B through its phosphorylation at Ser177 and Ser181 to promote the phosphorylation of inhibitors of kappa B (IBs), triggering their ubiquitination and degradation to active the nuclear factor kappa-B (NF-B) cascade

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Future clinical trials are urgently needed to determine optimal dosage regimens, establish dose-response relationships, and assess the long-term safety of EC supplementation