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Patologie del sistema nervoso Non comune: Cefalea Non nota: Convulsioni *, Capogiro Patologie cardiache Non nota: Palpitazioni Patologie vascolari Non comune: Ipertensione, Ipotensione Patologie respiratorie, toraciche e mediastiniche Non nota: Dispnea Patologie gastrointestinali Comune: Vomito, Nausea, Diarrea, Dolore addominale Non comune: Disgeusia, Dispepsia, Bocca secca Patologie della cute e del tessuto sottocutaneo Non comune: Odore delle cute anormale ** Non nota: Prurito, Eruzione cutanea Patologie del sistema muscoloscheletrico e del tessuto connettivo Non comune: Spasmi muscolari Non nota: Miastenia***, Tensione muscolare Patologie sistemiche e condizioni relative alla sede di somministrazione Non comune: Dolore toracico, Sentirsi strano, Piressia, Reazione in sede di iniezione**** Esami diagnostici Non comune: Pressione arteriosa aumentata Molto raro: Aumento dellINR*****

Gkika, N

This potentiating effect, comparable to that of chlorpromazine, a known inhibitor, suggests that the metabolites present in EEMC (probably alkaloids and/or flavonoids) act as efflux pump inhibitors (Coutinho et al., 2010)