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Other studies have shown that selenocysteine in GPx significantly delays human amyloid- 2 -induced paralysis, which is positively correlated with the incidence of Alzheimers disease and recovers -amyloid-induced toxicity and reduces the cellular level of EOS, by positively affecting life span and age-related pathophysiological alterations [67, 68]

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however, Mn can also instigate autophagic flux and dysfunction, especially under conditions of low Mn levels [29]

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