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People with a heterozygous MTHFR have one normal gene and one altered gene

[DOI] [PMC free article] [PubMed] [Google Scholar] 321.Chabosseau P., Woodier J., Cheung R., Rutter G.A

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However, the amounts obtainable from diet (estimated at 12 mg/day from a typical mixed diet) are far below therapeutic dosages used in clinical studies (3001,800 mg/day) [1][2]