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Similarly, in this study, the addition of GSH caused auxin input vector AUX related genes to be downregulated, transcription suppressor Aux/IAA to be activated, related genes to be upregulated, and auxin response factor ARF to be inhibited, thus inhibiting auxin signal transduction and improving cadmium tolerance of potato

While these effects are not evidence of addiction, they do indicate that the brain and nervous system can adapt to long-term SSRI use