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Phytochemistry 66, 12731284

Probiotic-based spores further combine carrier stability with the immunomodulatory properties of beneficial microbes, which makes them especially attractive for oral vaccination strategies that aim to reduce cold-chain dependence and manufacturing costs [228]

doi: 10.1371/journal.pone.0176391 71 TrevinoMBMachidaYHallingerDRGarciaEChristensenADuttaSet al

Bioinformatics studies (molecular docking simulation) revealed that GS binds to FXR and nuclear factor-kappa B (NF-B) and it docks into two non-canonical binding sites of FXR, helix 1-loop-helix 2 loop and parts of helixhelix 8 including helix 8-loop-helix 9 (Meyer et al., 2005