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As attempts to answer these questions, the present study is firstly aimed to determine whether the key hepatic enzymes and the redox-active metal ion involved in metabolic regulation [such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), and the ferrous ion (Fe 2+ )] would significantly be improved in animals suffered from CSD and received ALA treatment

However, more recent findings suggest NAD+ therapy might work even better when paired with a compound called 5-Amino-1MQ

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109 It is important to note that long-term, high-dosage use of licorice can cause sodium and water retention as well as potassium loss that may lead to increased blood pressure and edema