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5-Amino-1MQ inhibits the NNMT enzyme, which increases intracellular NAD+ availability and reactivates mitochondrial fat oxidation pathways the weight loss occurs through increased cellular energy expenditure without reducing appetite

B12 has been suggested to improve metabolic functions

Several complex I inhibitors have been evaluated clinically and discontinued due to neurotoxicity and adverse side effects (IACS-010759, Tamoxifen, Piericidin A, Phenformin) (76, 77)

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Stay Hydrated Drinking enough water daily is essential for optimizing fat metabolism and boosting your energy