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( e ) Comparison of key metabolites (choline, betaine, GSH, l-citrulline, and -aminobutyric acid) between Cx3cr1-CreER;DTA mice and controls

These aggregates are required for caspase-1-mediated IL-1 and IL-18 secretion, highlighting the role of CD14 high CD16 monocytes in COVID-19-related inflammation

It is implicated in the processes of tumor invasion and metastasis, and its elevated activity is often correlated with a reduction in patient survival times, highlighting its significance as a prognostic indicator in cancer (153)