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55(2): 20311 Mai I, Stormer E, Bauer S, et al

In advanced colorectal cancer [21] and p53-inactivated lung tumors [22], diminished expression of DDX3 was observed, correlating with poor prognosis in patients, while in vitro experiments, loss of DDX3 promoted soft-agar growth and invasion

Complementary analyses included protein-protein interactions (PPI) network analysis, therapeutic efficacy evaluation, differential gene expression assessment, and prognosis evaluation

Furthermore, cytokines and chemokines released by dying tumor cells following ADC treatment can recruit and activate various immune cells, including macrophages and natural killer (NK) cells, thereby further promoting antitumor responses (50)