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Cysteine anabolism and its interplay with other metabolic pathways in cancer De novo cysteine synthesis The de novo synthesis of cysteine occurs through the trans-sulphuration pathway of the methionine cycle, which also involves serine (Fig

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Although the diagnosis and preventative strategy may be rather straightforward, much is unclear about the pathophysiology and heterogeneity of this inherited genetic condition that underlies the severity of neonatal hyperbilirubinemia