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doi: 10.18632/oncotarget.20234

The Lancet , 392 (10156), 1423-1433

Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium

Moderate-affinity interactions generally promote productive transport, whereas excessively strong binding may result in receptor retention and lysosomal degradation rather than BBB passage (Kochman et al., 2026)