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Kang L, Zheng HX, Zhang M, Yan S, Li L, Liu L, et al

Salix Pharmaceuticals

However, some tumor cells can use glutathione peroxidase 4 (GPX4), a lipid repair enzyme, to decrease LPO accumulation by converting toxic LPO to non-toxic lipid alcohols in the presence of glutathione (GSH), thereby protecting themselves from ferroptosis [18, 19]