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For example, a man with low progressive motility may increase the dose slowly over 8 to 12 weeks while repeating semen analysis at 3-month intervals

Mutat Res 674(12):322 Frand AR, Kaiser CA (1998) The ERO1 gene of yeast is required for oxidation of protein dithiols in the endoplasmic reticulum

Interleukin-10 gene-deficient mice develop a primary intestinal permeability defect in response to enteric microflora

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Considered as primary mechanosensors on ECs, signaling through both integrins and cell-cell adhesion molecules can lead to increases in expression of mechanotransductive factors including ERK, Src, and PI3K/Akt, among others (231235)