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Moreover, recent research studies have also found that 1,25 dihydroxy vitamin D 3 ( 4 ) is considered as a transcriptional regulator of endothelial nitric oxide synthase, which leads enhanced endothelial nitric oxide (NO) production (Charoenngam and Holick 2020)

Progression of this disease into nonalcoholic steatohepatitis (NASH), cirrhosis, liver failure, and hepatocellular carcinoma in combination with its widespread incidence thus makes NAFLD and its related pathologies a significant public health concern