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China has the highest number of prevalent cases of stroke in the world, affecting ~3 million people (Wang W

Nat Rev Mol Cell Biol 7 : 505516

The activation of Na + -glucose cotransport requires MLCK upregulation to increase paracellular permeability

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Both enzymes can apparently feed into the NMT1 pathway with METAP2 being NAC independent, therefore possibly benefitting from the NAC recruitment activity of NMT1 in the next step