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thermodenitrificans where a homotetrameric precursor is initially produced, which underwent autocatalysis after incubation at 45C for 48 h ( Analysis of the recently solved crystal structure of the T399A precursor mimic of BlGGT gave interesting insights

Health 3 , 763771 (2025)

While mechanistically enigmatic, phenylacetylglutamines robust functional validation demands urgent mechanistic dissection to assess druggability, while serving as a caution against premature clinical extrapolation from correlative findings alone

While these metabolic alterations are dictated by numerous factors, including the genetic alterations in the tumour and the tumour environment or tissue of origin, recent attention has focused on the role of serine metabolism in supporting cancer cell growth 2

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