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Yet, they have to adapt to this challenge in order to maintain the capacity for tumor progression

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This phenomenon has been observed to occur through the mediation of the toll-like receptor 4 (TLR4)/NF-kB pathway

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designed a series of nucleoside-derived inhibitors, among which compound 6 demonstrated exceptional inhibitory activity in the double-digit nanomolar range against the N 7-MTase NSP14

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