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They are most effective in a comprehensive weight loss plan with a healthy diet, regular exercise, and lifestyle changes

People over 65 Age-related changes in stomach acid production reduce the ability to absorb B12 from food

For that reason, an untreated pernicious anemia often leads to neurological damage, which should explain why so many patients with neurological disorders such as Alzheimer, multiple sclerosis, peripheral neuropathy, and Bells Palsy, benefit from B12 shots

[99] A person with cobalamin C disease, a rare autosomal, recessive, inheritance disease which results in combined methylmalonic aciduria and homocystinuria), [100] can be treated with intravenous or intramuscular hydroxocobalamin

Mechanism of action [edit] Vitamin B 12 refers to a group of compounds called cobalamins that are available in the human body in a variety of mostly interconvertible forms