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IGF-1, LR3 and Other Supplements for Bodybuilding Bodybuilders and other athletes have shown interest in IGF-1 because it helps build muscle

A mouse study examined 5A-1MQ combined with a reduced-calorie diet and microbiome changes

Finally, there are other neurotrophic factors that have shown dopaminergical neuronal protection in Parkinson-like models, including hepatocyte growth factor (HGF), mesencephalic astrocyte-derived neurotrophic factor (MANF), cerebral dopaminergic neurotrophic factor (CDNF), granulocyte colony-stimulating factor (G-CSF), and platelet derived growth factor (PDGF-CC) [31-32, 135-136]