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The animals were bred in the animal house of the Department of Biochemistry, Michael Okpara University of Agriculture, Umudike under standard conditions (2527 C, 12 h natural light-dark cycle) and fed with commercially available rat pellets and water ad libitum

Riboflavin status modifies the effects of methylenetetrahydrofolate reductase (Mthfr) and methionine synthase reductase (Mtrr) polymorphisms on homocysteine