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Vitamin B12 cyanocobalamin supplements are made by using bacteria grown on a cobalt-enriched medium in a laboratory, producing vitamin B12 as natural as found in dairy, eggs, and meats

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To achieve this outcome, we used Target-AID, which we previously developed as one of the first-generation CT base editors that is highly active in mammalian cells and has a narrow CT editing window in the gRNA target site 35,37