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Logistic regression models reporting OR with 95 % CI were used to analyse the longitudinal association of folate and B 12 categories with depression

Expected milestones during therapy: Baseline assessment and initial labs Early symptom change (26 weeks) Objective lab improvement (612 weeks) Dose optimization and protocol refinement (3 months) Long-term maintenance or tapering plans (612 months) Expectations While most patients experience progressive symptom relief, some begin to notice changes within 2 to 6 weeks, with measurable reduction in inflammation present by 8 to 12 weeks

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Lipoxygenases (LOXs) are important enzyme systems that mediate the formation of ferroptosis peroxides