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Blood or CSF lactate and pyruvate are elevated with normal lactate to pyruvate (L/P) ratio (reference range: 10 to 20), differentiating primary pyruvate dehydrogenase complex deficiency from primary mitochondrial disorders, such as those due to electron transport chain dysfunction where L/P ratios are generally elevated

The his-tagged GPX4 was eluted with an increasing imidazole step-gradient (100250 mM)

Ipamorelin was designed as a synthetic agonist of this receptor pathway

Pretreatment with DNQX had no significant effect on the GSH/GSSG ratio and the chilling tolerance in RBOH1 -silenced plants and GSH1 - and GSH2 -cosilenced plants ( 2 O 2 -GSH cascade