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13 C 6 - 15 N 2 -labeled cystine (CNLM-4244-H-PK) was from Cambridge Isotope Laboratories (Tewksbury, MA, USA)

It is widely understood that BC does not arise from a single genetic abnormality but rather involves a perturbation in a broad array of cell types, including cancerous cells, immune cells, epithelial cells, vascular cells, stromal cells, and hormones

This underscores cysteine as the primary limiting factor for CoA biosynthesis (Fig

Nfbib, NF- B inhibitor-