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Dauer: 45 Minuten POWER: Der ideale Einstieg

Within the -loop, residues 154-200 are predicted to fold into a two-helical element (described as helices 4a 5a here), flanked by hinge regions (described here as N- and C-hinges) ( Figure 6B ) believed to promote transition of the GDAP1 -loop between closed and open states(Sutinen et al., 2022)