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In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation

4.3 Antioxidants in chemotherapy 4.3.1 Impact on chemotherapy-induced lipid peroxidation One of the important treatments for cancer, which is commonly known as chemotherapy, causes severe oxidative stress on normal tissues, and there is increased lipid peroxidation [136]